曹桂珠,康滢蓥,李瑶,李红霞

• 1:南开大学医学院
• 2:天津医科大学第一中心医院麻醉科

摘要(Abstract)：

微小RNA(miRNA)是一种小的非编码RNA分子，通过与信使RNA特异结合，从而在转录后基因调控中发挥作用。近年的研究发现，miRNA在肾脏疾病中扮演着重要的角色，它们不仅参与疾病的发生与发展，作为用于鉴别诊断和预后预测的非侵入性生物标志物，还调节多种免疫细胞亚群的发育和功能，包括T淋巴细胞、B淋巴细胞和自然杀伤细胞等。本文总结了近五年来miRNA相关免疫调节在肾脏疾病中的研究进展，为miRNA的临床应用转化提供理论参考。

关键词(KeyWords)： 微小核糖核酸;免疫调节;肾脏疾病;移植免疫

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 曹桂珠,康滢蓥,李瑶,李红霞

DOI: 10.19460/j.cnki.0253-3685.2025.09.020

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